Posted on : 27 Jan 2020Views: 560
- Under in vitro conditions, Nilavembu Kudineer (a Siddha medicine) was found to provide protection against Chikungunya virus while it was effective as a treatment during acute phase of Dengue infection. Dengue subtype-2, which is the most prevalent subtype in India, was used for testing the formulation. There was significant antiviral activity of the formulation at 3% of human dose onwards. Currently, there is no treatment for dengue and chikungunya.
- The Tamil Nadu government had distributed Nilavembu Kudineer concoction to treat people infected with dengue during the outbreak in late 2017.
- A team of researchers from the International Centre for Genetic Engineering and Biotechnology (ICGEB), Delhi found that the Nilavembu Kudineer formulation was modulating the host response in the case of both chikungunya and dengue virus but in a different manner. The mode of action of the concoction is antiviral in the case of dengue while immuno-modulatory in chikungunya infection.
- Safety studies showed that Nilavembu Kudineer concoction was non-toxic starting from 3% (about 1.8 milligram per milliliter) of human dose. However, the researchers found that andrographis, which is the active ingredient of Nilavembu Kudineer, when used alone was extremely toxic at 3% of human dose. Human dose is prepared by mixing 5 grams of Nilavembu Kudineer in 240 ml of water. It is then boiled and reduced to 30 ml and consumed.
Article Related Questions
Nilavembu Kudineer, seen in news recently, relates to
1.A Siddha medicine providing protection against Chikungunya and Dengue.
2.A fruit bat species responsible for Nipah outbreak in Kerala.
3.An invasive plant species threatening Indian rhinos in Assam.
4.A fibre-yielding, perfectly sustainable rhizome.
Right Ans : A Siddha medicine providing protection against Chikungunya and Dengue.