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Alzheimer’s disease

Posted on : 25 Feb 2020

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  • Alzheimer’s disease is an irreversible, progressive brain disease that slowly destroys memory and thinking skills, and eventually, the ability to carry out the simplest tasks of daily living.
  • Alzheimer's disease is the most common form of dementia which is more common in older individuals.
  • Dementia is a disorder characterized by serious loss of cognitive ability in a previously unimpaired person.
  • Alzheimer is named after a German psychiatrist Louis Alzheimer in 1906.
    • Scientists have not yet understood the exact cause of Alzheimer's disease. It is postulated to have multifactorial etiology like:
    • The Apolipoprotein E (ApoE) gene is implicated in Alzheimer’s disease. This gene has several forms. One of them, ApoE ε4, seems to increase a person’s risk of getting the disease.
    • However, carrying the ApoE ε4 form of the gene does not necessarily mean that a person will develop Alzheimer’s disease, and people carrying no ApoE ε4 can also develop the disease.
    • Scientists around the world are searching for other genes that may increase a person’s risk for developing Alzheimer’s disease.
      • Environmental/ Lifestyle factors: Diseases like heart disease, stroke, high blood pressure, diabetes, obesity, hyperlipidemia etc. have also shown to be linked with the Alzheimer's disease.
      • There is no definitive evidence to support that any particular measure   is effective in preventing. However, there are certain steps that could be taken which may help to delay the onset of dementia such as stayinghealthy.

Article Related Questions

  1. Consider the following statements regarding Alzheimer’s disease
    1.Alzheimer's disease is the most common form of dementia which is more common in older individuals.
    2.Monitoring antioxidant Glutathione levels in brain can offer a way to detect signs of this disease.
    Which of the statement(s) given above is/are correct?

  2. 1.1 only

    2.2 only

    3.Both 1 and 2

    4.Neither 1 nor 2

    Right Ans : Both 1 and 2

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