3D bio-printing/ Additive manufacturing
Posted on : 17 Jan 2020Views: 283
- Bio-printing is an additive manufacturing process where biomaterials such as cells and growth factors are combined to create tissue-like structures that imitate natural tissues.
- Bio-ink is used to create these structures in a layer-by-layer manner.
- Bio-ink: Bio-ink is a combination of living cells and a compatible base, like collagen, elastin, gelatin, hyaluronan, silk, alginate or nanocellulose.
- But the process can essentially be summarized into three key steps:
- Pre bio-printing involves creating the digital model that the printer will produce. The technologies used are computed tomography (CT) and magnetic resonance imaging (MRI) scans.
- Bio-printing is the actual printing process, where bio-ink is placed in a printer cartridge and deposition takes place based on the digital model.
- Post bio-printing is the mechanical and chemical stimulation of printed parts so as to create stable structures for the biological material.
- Medicine and Bio-engineering: Advancements in the production of cartilage tissue for use in reconstruction and regeneration.
- The process has potential to eradicate in future the need of organ donation and transplantation. Treatment for diseases can be tested using artificially affected tissues.
- Bone tissue regeneration as well as prosthetics and dental applications.
- Pharmaceutical testing and reduced need for animal trials.
- Cosmetic surgery
- The vasculature still has to be developed to allow lab skin to integrate with the human body’s blood vessels.
- Stem cell engineering hasn’t yet evolved to grow all cells of an organ in a personalized way to avoid rejection by recipient’s immune.
- Current not evolved to ensure that a lab organ works well with all other human organs.
Article Related Questions
Recently, many developments have been made in the field of bio-printing. Which of the following is not a limitation of 3D bio-printing?
1.The abundant and branched nature of the vasculature is difficult to reproduce
2.Risk of immune rejection
3.Accurately printing tissues on the micro-scale
Choose the correct answer
2.1 and 2 only
4.1, 2 and 3
Right Ans : 3 only